ffpe tissue sections with cd31 (Cell Signaling Technology Inc)
Structured Review

Ffpe Tissue Sections With Cd31, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ffpe tissue sections with cd31/product/Cell Signaling Technology Inc
Average 86 stars, based on 1 article reviews
Images
1) Product Images from "GLUT1 expression, lymphocyte distribution and CD3 + T-cell metabolic subsets as predictive markers of response to immunotherapy in advanced melanoma"
Article Title: GLUT1 expression, lymphocyte distribution and CD3 + T-cell metabolic subsets as predictive markers of response to immunotherapy in advanced melanoma
Journal: Journal of Experimental & Clinical Cancer Research : CR
doi: 10.1186/s13046-025-03637-8
Figure Legend Snippet: Associations between GLUT3 expression and immunotherapy response. A Representative multiplex image demonstrating expression of GLUT1 on SOX10 + tumor cells and CD31 + vessels, and GLUT3 expression on SOX10 + tumor cells and CD3 + T-cells. B 100% stacked bar plots illustrating GLUT1 + and GLUT3 + melanoma subsets as proportions of total SOX10 + melanoma cells. C 100% stacked bar plots illustrating GLUT1 + and GLUT3 + T-cell subsets as proportions of total CD3 + T-cells. D Bar plot showing no significant difference in the proportion of GLUT3 + melanoma between responders and non-responders. E Bar plots demonstrating significantly higher proportions of intratumoral GLUT3 + T-cells and GLUT3 + GLUT1 − T-cells in responders compared to non-responders. Error bars represent median ± 95% CI. * p < 0.05, ns – non-significant
Techniques Used: Expressing, Multiplex Assay
Figure Legend Snippet: Associations between spatial locations of CD3 + T-cell subsets, CD31 + vessels and clinical outcomes. A Multiplex IF image and corresponding spatial plot showing locations of CD3 + T-cells (orange), GLUT3 + cells (green), CD31 + vessels (magenta) and SOX10 + melanoma cells (red). B Multiplex IF plot illustrating metabolic zonation pattern, with GLUT1 + and GLUT3 + melanoma located further away from CD31 + vessels. Bar plots showing all SOX10 + melanoma cells, GLUT1 + melanoma and GLUT3 + melanoma to be significantly further away from CD31 + vessels in tumors with metabolic zonation compared to those without metabolic zonation. C Bar plots showing CD3 + T-cells in closer proximity to GLUT3 + melanoma cells in responders compared to non-responders and significantly higher proportions of CD3 + T-cells within 20 µm of a GLUT3 + melanoma cell in responders. D Bar plots showing no significant differences in the average distances or spatial proximity of CD3 + , CD3 + GLUT1 + or CD3 + GLUT3 + T-cells to CD31 + vessels between responders and non-responders. Error bars represent median ± 95% CI. * p < 0.05, ** p < 0.01, ns – non-significant
Techniques Used: Multiplex Assay